1,3-Dipolar cycloaddition

1,3-dipolar cycloaddition is a term for certain chemical reactions in organic chemistry. It involves cycloaddition, in which a 1,3- dipolar molecule or fragment is involved. As mesomeriestabilisierter 1,3 -dipole thereby ozone, azides, Diazoalkanes, nitrile oxides, nitrile imines, nitrones et cetera are added to alkenes or alkynes. The atom economy of 1,3 - dipolar cycloaddition is consistently excellent.

An example of a 1,3-dipolar Huisgen cycloaddition is the reaction. This reaction was previously known, but was only able to Rolf Huisgen elucidate the exact mechanism on the basis of his systematic studies of the 1,3 - dipolar cycloaddition. The reaction is usually carried out with an azide and an alkyne. Therefore it is also called the azide / alkyne click reaction ( click chemistry ).

A double 1,3- dipolar cycloaddition of the ozonolysis: this is only the 1,3- dipole ozone and, after the breaking of C-C as well as a O-O bond, then added the 1,3-dipolar carbonyl.