AEBSF

4 - (2 -aminoethyl) benzensulfonylfluorid

  • 34284-75-8
  • 30827-99-7 (as HCl)

White solid

  • 203.24 g.mol -1
  • 239.70 g · mol -1 ( as HCl)

Fixed

175-177 ° C ( as hydrochloride)

Poorly in water (10 g · l-1 at 20 ° C as hydrochloride)

Risk

Template: Infobox chemical / molecular formula search available

AEBSF is the abbreviation for 4 - (2 -aminoethyl) benzensulfonylfluorid (trade name of the hydrochloride: Pefabloc SC ®), a water-soluble serine proteinase inhibitor. It inhibits proteases, such as chymotrypsin, kallikrein, plasmin, thrombin and trypsin.

AEBSF has a similar spectrum of action, such as PMSF ( phenylmethylsulfonyl fluoride ), but is much more stable, especially at low pH values. Are solutions having a concentration of 0.1-1 mM are typically used.

CAS registry number Dangerous Substances Directive (67/548/EEC)
32061
de