Aldicarb

2 -methyl-2 -(methylthio ) propionaldehyde -O-( N- methylcarbamoyl ) oxime

White crystalline solid

Fixed

1.195 g · cm -3

100 ° C.

225 ° C at 6.7 mbar

0.00013 hPa ( 20 ° C)

Sparingly soluble in water (6 g · l-1 at 20 ° C)

Risk

• 0.5 mg · kg -1 ( LD50, rat, oral)
• 1400 mg · kg -1 ( LD50, Rabbit, transdermal)

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Aldicarb is a plant protection agent is selected from the family of the carbamate, which is used as an insecticide, acaricide and nematicide. The highly toxic compound is used for soil treatment.

History

Aldicarb was developed in 1962 by Union Carbide.

Production and representation

Aldicarb can be prepared starting from isobutylene, by reaction with nitrosyl chloride or sodium nitrite and further reacting the resulting intermediate with sodium methanethiolate and then extracted with methyl isocyanate.

Properties

Aldicarb is a crystalline white solid.

Use

Aldicarb comes as a 5, 10 or 15 % granule in the trade. In Germany and Austria no aldicarbhaltiges pesticide is approved. In Switzerland, the application of aldicarbhaltigen pesticides is limited to combating the Rübenkopfälchens in sugar beet cultivation. Aldicarb is not on the list of approved in the European Union pesticides.

The main applications are in the cultivation of cotton, soybeans and peanuts.

Toxicology

Aldicarb inhibit the enzyme cholinesterase and thus increases the conduction between cholinergic nerve cells with the symptoms of severe parasympathetic activity as a result. The substance is highly toxic in both oral ingestion and contact with skin. The toxic effect occurs rapidly and lasts between 4 to 12 hours. LD50 in rodents is from 0.5 to 1.5 mg / kg body weight when the aldicarb was administered dissolved in water or oil. For dry granulate the LD50 is about 7 mg / kg body weight. There is no evidence of a teratogenic, mutagenic or carcinogenic effect.