Alexander Varshavsky
Alexander Varshavsky ( born November 8, 1946 in Moscow ) is a Russian- American biochemist and professor at the California Institute of Technology.
Life
Varshavsky earned a bachelor's degree in 1970 in chemistry at the University of Moscow in 1973 and a Ph.D. of Biochemistry at the Institute for Molecular Biology in Moscow. From 1973 to 1976 he was a research assistant there. Varshavsky 1977 emigrated to the United States, where he Department of Biology at the Massachusetts Institute of Technology in the first junior professor took over (1977 Assistant Professor, Associate Professor in 1980 ) and 1986 was a full professor. In 1992 he moved to the California Institute of Technology, where he is Howard and Gwen Laurie Smits Professor of Cell Biology.
Work
By genetic studies of yeast and cell cultures of higher organisms could Varshavsky explain various meanings of the ubiquitin system in the degradation of proteins by the N- End Rule, an important role in the cell cycle, in apoptosis, the malignant transformation of the inflammatory regulation, and the immune response plays.