Amide

Amides are chemical compounds that are formally derived from ammonia (NH3 ) can be derived: a hydrogen atom of ammonia (usually an acyl radical ) is replaced by an acid radical.

  • Ionian amides are salts of ammonia, such as sodium amide, NaNH2.
  • Covalent amides are formally derived from ammonia or amines and (mostly organic ) acids from by formally the hydroxyl group of the acid is replaced by an N- R1R2 group. They have the general structural formula R -X ( = O) n- N- R1R2. R, R1 and R2 may in this case be hydrogen, or other residue, X is a non-metal.

An isomeric structure in which the double bond is not between carbon and oxygen, but also between carbon and nitrogen, and at the same time there is a hydroxy group form the amidate.

Covalent amides

Covalent amides can be found than among other

  • Carboxamides derivatives of carboxylic acids, Lactams as cyclic carboxamides
  • Imides as secondary carboxamides
Substituent Cyclophosphamide Ifosfamide Integrated Authority File
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