Bioavailability

Bioavailability is a pharmacological measure of the proportion of an agent that is unchanged in the systemic circulation (especially in the bloodstream ) are available. It indicates how quickly and to what extent the material (mostly drug ) was added ( absorbed ) and is available at the site. Bioenhancers may increase the bioavailability of a substance.

For drugs that are administered intravenously, bioavailability is defined as 100 %. The absolute bioavailability indicates the bioavailability of an applied in an arbitrary manner (eg orally ) substance compared with intravenous administration. The observed after oral administration bioavailability is also called oral bioavailability. The relative bioavailability compared with a dosage form of another administration form (e.g. a tablet with a solution).

Bioavailability is also an important variable pharmacokinetics in the context of drug approval.