Catabolism

Catabolism (Greek καταβολισμός, katabolismós, originally " resignation, loss of strength " ) is called to simple molecules for detoxification of the body for energy and the reduction of metabolic products of complex. With the anabolism it is connected by the coupling of energy: The energy obtained here is used there to build complex molecules. Anabolism and catabolism, parts of metabolism.

Regulation

Catabolic and anabolic reactions take place in the cell, not simultaneously. This is among other things guarantees that the enzymes of a catabolic branch of the pathway (glycogen degradation, lipolysis) are activated by kinase activity, which are the anabolic branch (glycogen or fat synthesis) but inactivated. By the action of phosphatases ( dephosphorylation ) are reversed this situation.

Catabolism is the appropriate body's response to stress. Since the body is its own source of energy, a destruction of body substance with a load always necessarily to some extent connected.

Pathophysiology

In the course of atrophy (eg, flaccid muscle paralysis), or even in acute necrosis (eg, heart attack, stroke) is an increased catabolism place in doping or physiological growth, however, it is lowered.