Chromosome 6 (human)
Chromosome 6 is one of 23 pairs of chromosomes in humans. A normal person has two nearly identical copies of this chromosome in most of its cells.
Decryption of chromosome 6
The chromosome 6 consists of 171 million base pairs. A base pair is the smallest information unit of DNA. The chromosome 6 containing about 5.5 % of the total DNA of a human cell. The identification of the genes on this chromosome is the part of the ongoing process of the human genome. On chromosome 6 are 1100-1600 genes.
Known genes on chromosome 6
The chromosome 6 contains the following genes:
- Factor XIII fibrin-stabilizing factor
- HSPA1A: Hsp70
- CDKN1A: p21
- PKHD1: Polycystic kidney and hepatic disease 1
- VEGF: Vascular Endothelial Growth Factor
- MHC / HLA: the major histocompatibility complex / human leukocyte antigen
- PARK2: parkinson protein 2, E3 ubiquitin protein ligase ( parkin )
Medical importance
With the genes located on chromosome 6, the following genetic diseases or symptoms are associated. These include:
- Autosomal recessive polycystic kidney disease ARPKD
- Chondrodysplasia punctata
- Dyslexia
- Hemochromatosis
- Dyslexia
- Multiple Myeloma
- Porphyria cutanea tarda
- Psoriasis vulgaris
- Sarcoidosis