Combination drug

As combination products ( Composita ) all drugs are called that contain multiple active ingredients. These drugs have in their composition have similar or completely different effects.

The combination of active ingredients an improved principal effect or an extension of the spectrum of action ( for example the combination of sulfonamides with trimethoprim ), and serves to reduce the side effects, as the active ingredients are present in each case in the lower doses. In some preparations, the concomitant use of two active ingredients is even required such as in progestin and estrogen in oral contraceptives.

Disadvantages

Combination preparations are often considered not optimal or even risky, since an over - or under-dosing of one or the other substance can be achieved by different modes of curves or action times. Are often criticized, among other things painkillers with caffeine, with the concern that a dependence can arise from caffeine; would be taken however, because of Engaging this is not so recognizes the analgesic substances.

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