Cosmid

As cosmids is called plasmids, called cos sites ( cohesive site) included. These are DNA sequences derived from the λ phage. These sections are at the ends of linear chromosomes and phage are respectively identical in sequence, but face each other ( inverted repeat ). About this DNA can form a ring ( circularize ) and is thus not degraded in the host cell.

Cosmids are packaged into phage structures of proteins, and so the foreign genes can be transduced in bacteria ( introduced ) are. Include the cosmids eg genes for antibiotic resistance, the transduced bacteria are able, in a culture solution despite addition of the respective antibiotic to survive and multiply. Cosmids are used to create gene libraries of a genome.

Swell

  • Bruce A. Voyles (2002) The biology of viruses 2nd ed ISBN 0-07-237031-9
  • Stryer, Lubert (1995 ) Biochemistry 4th ed ISBN 0-7167-2009-4
  • Nucleic acid
  • Microbiology
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