DeMayo reaction

The De Mayo reaction is a reaction names of organic chemistry and named after Paul Jose de Mayo ( 1924-1994 ). In this reaction, a 1,5- diketone can be obtained by a photochemical reaction takes place of an alkene with an enolisierbarem 1,3-diketone. The reaction is classified as a domino reaction.

Mechanism

The enolizable 1,3-diketone 1 reacts with an alkene in a [2 2 ] cycloaddition. The result is a β -hydroxy ketone 3 This reaction step is followed by a retro-aldol reaction, which leads to the opening of the cyclobutane ring 3. About a keto -enol equilibrium, a 1.5 - diketo forms are mechanistically 5