Denham Harman

Denham Harman ( born February 14, 1916) is an American biogerontologist and professor emeritus at the University of Nebraska Medical Center in Omaha. Harman is considered the father of the theory of free radicals.

CV and work

Harman studied at the University of California, Berkeley chemistry. There he received his Bachelor of Science and Ph.D. in 1943. Meanwhile, he spent six years in the field of organic chemistry at Shell Oil. He then studied medicine at Stanford, where he received his MD in 1954. In 1958 he received a professorship at the University of Nebraska Medical Center.

In 1954 he developed at Berkeley at the Faculty of Medical Physics his theory of free radicals, which he published in 1956.

The 1970 co-founded Harman American Aging Association (AGE) gives the since 1978 Denham Harman Research Award. He also co-founded the International Association of Biomedical Gerontology.

Harman, who has four children and is married to Helen, has been proposed several times for the Nobel Prize in Physiology or Medicine.

Literature (selection )

  • D. Harman: Origin and evolution of the free radical theory of aging: a brief personal history, 1954-2009. In: Biogerontology [Electronic publication ahead of print], 2009 PMID 19466577
  • D. Harman: Alzheimer 's disease pathogenesis: role of aging. In: Ann N Y Acad Sci 1067, 2006, pp. 454-460. PMID 16804026 (Review)
  • Harman D.: Free radical theory of aging: an update: Increasing the functional life span In: Ann NY Acad Sci 1067, 2006, pp. 10-21. PMID 16803965 (Review)
  • D. Harman: The free radical theory of aging. In: Antioxid Redox Signal 5, 2003, pp. 557-561. PMID 14580310 (Review)
  • Harman D.: Aging: overview. In: Ann N Y Acad Sci 928, 2001, pp. 1-21. PMID 11795501 (Review)
  • Harman D.: Free radical theory of aging. In: Mutat Res 275, 1992, pp. 257-266. PMID 1383768 (Review)
  • D. Harman: The biologic clock: the mitochondria? In: J Am Geriatr Soc 20, 1972, p 145-157. PMID 501 663
  • D. Harman: Secondary amyloidosis and antioxidants. In: The Lancet 8194, 1980, pp. 593 PMID 6106771
  • D. Harman: mutation, cancer, and aging. In: The Lancet 7170, pp. 200-201. PMID 13711615
Senescence Omaha, Nebraska Mutation Research (journal) Digital Object Identifier
227428
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