Diisopropylamine

  • Bis ( prop-2- yl ) amine
  • DIPA
  • Bis (1- methylethyl ) amine

C04AX37

Highly volatile, flammable, colorless liquid with an amine-like odor

Liquid

0.72 g · cm -3

-61 ° C

82 ° C

85 hPa ( 20 ° C)

Soluble in water (> 30 g · l-1 at 20 ° C)

1.392 (20 ° C)

Risk

420 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Diisopropylamine is a chemical compound selected from the group of the secondary aliphatic amines.

Properties

Diisopropylamine is in the form of a volatile, corrosive, flammable, colorless liquid with an amine-like odor. It decomposes with nitrogen oxides are released at higher temperatures.

Use

Diisopropylamine is used as a catalyst, a solvent and as an intermediate in the preparation of corrosion inhibitors, and other compounds (such as diisopropylethylamine ), and the amine used in the laundry, and Sonogashira coupling. In medicine, diisopropylamine is used as an arteriolar vasodilator. Diisopropylamine is used in the organic chemistry as the starting compound for the preparation of low nucleophilic strong base lithium diisopropyl amide (LDA).

Safety

The vapors of diisopropylamine may form (-7 ° C, ignition temperature 285 ° C flash point) with air to form an explosive mixture. With oxidizing agents, acids, organic compounds of aluminum and a strong reaction can be carried out. In reaction with nitrosating reagents to carcinogenic N -nitrosamines can form.

Derivatives and related compounds

  • Lithium diisopropylamide ( lithium salt of diisopropylamine )
  • Isopropylamine
  • Propylamine
  • Diisopropylethylamine ( Hunig base )
  • N -nitroso -diisopropylamine
126809
de