Dithranol

• D05AC01
• D05AC51

Yellow crystalline solid

Antiseptic

178-181 ° C

Attention

Template: Infobox chemical / molecular formula search available

Dithranol in the U.S. referred to as anthralin, in Germany as anthralin, is an important drug which is used to treat psoriasis (psoriasis ) are available. It belongs to the group of chemically Hydroxyanthrone.

Properties

It was first synthesized in 1916. It was the first developed specifically for the treatment of psoriasis drug and was initially applied in topical preparations in concentrations from 0.25 to 1 % on psoriatic skin with lengths of stay of up to 24 hours. Meanwhile, there is also used at concentrations up to 4 % in the so-called minute therapy. The most common side effects include severe irritation and reversible brown staining of the treated skin areas. In addition, there is the treatment of verruca vulgaris available, here is next to the keratolytic effect and the local irritation exploited in terms of induction of inflammation. Similarly, one can use dithranol in the treatment of alopecia areata.

Besides its use as a drug it is used in the MALDI mass spectrometry matrix material.

Trade names

Micanol (D, A); CH: only as substance

Psoradexan (D), Psoralon (D)