Ernest William Goodpasture

Ernest William Goodpasture ( born October 17, 1886 in Clarksville, Tennessee; † September 20, 1960 in Nashville, Tennessee) was an American pathologist.

Goodpasture's pioneering work on the growth of viruses, bacteria, and rickettsiae in the chick embryo and developed methods to stimulate such growth. His studies have led to a better understanding of host-parasite relationships, opening up new possibilities for the treatment of infectious diseases.

Life

Goodpasture graduated from Vanderbilt University in Nashville, Tennessee, a bachelor and 1912 the MD (as graduation from medical school ) at Johns Hopkins University in Baltimore, Maryland. He then worked with William Henry Welch and George H. Whipple in the local pathology, 1912-1914 as Rockefeller Fellow. From 1915 to 1917 Goodpasture worked as a pathologist at the Peter Bent Brigham Hospital in Boston, Massachusetts. 1917 Goodpasture was Assistant Professor of Pathology at Harvard University in Cambridge, Massachusetts. In 1922 he was appointed head of the William H. Singer Memorial Research Laboratory in Pittsburgh, Pennsylvania, appointed before the Chair of Pathology at Vanderbilt University in Nashville, Tennessee in 1924. In 1955 he became Professor Emeritus, but still worked as scientific director of the Pathology of the Armed Forces Institute of Pathology at Walter Reed Army Medical Center in Washington, DC.

Work

1919 Goodpasture described a combination of glomerulonephritis with pulmonary hemorrhage; the disease was later called Goodpasture's syndrome. Also, is named the McCullum - Goodpasture stain after him ( and William George MacCullum ), a method for staining Gram- negative bacteria.

1931 Goodpasture developed a method to cultivate viruses and rickettsiae in the chick embryo. This made ​​possible the production of vaccines against chicken pox, smallpox, yellow fever, typhus, Rocky Mountain spotted fever and other pathogens that can be cultured so.

Further work Goodpastures dealt with the formation of fibrinogen, with hemorrhagic pancreatitis, herpes simplex, influenza, yaws, rabies and general questions of tumor formation.

From 1942 to 1945, Goodpasture Vice - Dean and 1945-1950 Dean of the Vanderbilt University. He was one of the editors of the American Journal of Pathology.

Awards (selection)

Further Reading

• J. R. Dawson: Ernest William Goodpasture. In: The American journal of pathology. Volume 38, February 1961, pp. 125-126, ISSN 0002-9440. PMID 13,720,324th PMC 1945009 (Free full text ). (PDF, 557 kB)
• Esmond R. Long: Ernest William Goodpasture 1886-1960. In: Biographical Memoir. National Academy of Sciences, Washington, 1965 ( PDF, 1.5 MB)
• Robert D. Collins: Ernest William Goodpasture: Scientist, Scholar, Gentleman. Hillsboro 2002 ISBN 978-1-57736-251-7