Hemoglobinuria

As hemoglobinuria excretion of hemoglobin is called ( the red blood pigment) by the kidneys, which can lead to if it were severe acute renal failure.

A hemoglobinuria occurs only when due to a massive hemolysis, the binding capacity of haptoglobin formed by the liver is depleted or at a reduced liver damage by a haptoglobin concentration in plasma at the same time the tubular absorption capacity of the kidneys is exhausted. With the elimination of hemoglobin in the urine changes color this dark.

The cause consists in an acute, usually massive hemolysis, as used in various hemolytic anemias, transfusion incidents, malaria and autoantibodies diseases (see cold agglutinins ) may occur.

However, until further evaluation ( medical history, other laboratory parameters, symptoms, course curve of hemoglobin excretion: continuous or intermittent or paroxysmal ) lead in the given case by the finding of a single hemoglobinuria for diagnosis, which ultimately may also be:

• Allergic hemoglobinuria
• Toxic hemoglobinuria
• Marschhämoglobinurie, Sporthämoglobinurie
• Intermittent hemoglobinuria Paroxysmal nocturnal hemoglobinuria
• Paroxysmal cold hemoglobinuria Dressler Harley 's disease