Hesperetin

• (S ) -2,3 -dihydro -5 ,7- dihydroxy- 2-(3 -hydroxy- 4-methoxyphenyl) -4H- 1-benzopyran -4-one
• (S ) -2,3 -dihydro -5 ,7- dihydroxy- 2-(3 -hydroxy -4-methoxyphenyl )-4- benzopyrone
• Hesperetol
• (S )-3 ',5,7 -trihydroxy -4'- methoxyflavanon

• 520-33-2
• 69097-99-0

Leaflet

Fixed

216-218 ° C

• Slightly soluble in water, benzene, chloroform
• Soluble in ethanol
• Soluble in dilute alkalis

Template: Infobox chemical / molecular formula search available

Hesperetin, the aglycone of hesperidin and belongs to the group of flavonoids.

History

Hesperetin in 1928 for the first time obtained by hydrolysis of hesperidin.

Occurrence

Hesperetin comes next before hesperidin in bowls of oranges and other citrus fruits.

Properties

The natural hesperetin is chiral. The specific optical rotation of the natural ( S) - ( -)- Hesperetins is -37.6 ° (C = 1.8 M in ethanol at 27 ° C).

Pharmacological action

Hesperetin inhibits lipid peroxidation as a powerful antioxidant and may protect against certain harmful influences ( neuroprotection ) neurons.

Furthermore, hesperetin and its metabolites reduce the lipid content of the blood, and there is also evidence of an inhibition of cholesterol biosynthesis.