Hexetidine

1,3-bis ( 2-ethylhexyl) -5-methyl - 1,3- diazinan -5-amine (IUPAC)

A01AB12

Colorless to pale yellow oily liquid

Antiseptic

0.8889 g · cm -3

8.3

Soluble in petroleum ether, methanol, benzene, acetone, n-hexane and chloroform, practically insoluble in water

Attention

1430 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Hexetidin is an antiseptic that is used in 0.1 or 0.2 % solution in the mouth and throat. It is available as a gargle and as a spray.

Chemical Properties

Hexetidine is a hexahydro- pyrimidine derivative. It is an amphiphilic compound.

Effect

Hexetidin has a broad spectrum antiseptic action against bacteria and fungi, but mainly against gram-positive bacteria. It also has local anesthetic, astringent and deodorizing effects.

Trade names

Drossadin (CH), Hexoral (D, A), Hextril (CH), Isozid -H ( A), Vagi -Hex (D, CH), Oraldene ( GB)