Iohexol

1-N,3-N-bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-triiodbenzen-1,3-dicarboxamid

V08AB02

White to off-white, hygroscopic powder

Contrast agent

• Very slightly soluble in water
• Slightly soluble in methanol
• Almost insoluble in dichloromethane

> 20,000 mg · kg -1 ( LD50, rat, oral)

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Iohexol is a mixture of several isomeric chemical compounds, which are among the haloaromatics and polyols. It is very soluble in water and is used in medicine under the trade name Omnipaque ® as iodine-containing contrast agents. Intravenously administered iohexol is used for visualization of blood vessels in the X-ray examination ( angiography ). Since the drug is completely excreted by the kidney, it is also suitable for excretory urography and determination of renal clearance.