Isoxazole
1,2- oxazole
Liquid
1.078 g · cm -3 ( 25 ° C)
93-95 ° C
1,427
Risk
42.1 kJ / mol
Template: Infobox chemical / molecular formula search available
Isoxazole is a derivative of furan and pyrrole nitrogen-containing heterocycle. In contrast to the isomeric oxazole, the oxygen atom is located adjacent to the nitrogen.
Isoxazolringe found in some natural products such as ibotenic acid. Isoxazoles also form the basis for a number of drugs, such as COX -2 inhibitor valdecoxib ( Bextra ).