K. C. Nicolaou

Kyriacos Costa Nicolaou ( born July 5, 1946 in Karavas, Cyprus) is an American chemist Cypriot origin.

Life and work

KC Nicolaou, born in Cyprus, the son of Helen and Costa Nicolaou, born Yettimi and grew up there. In 1964 he moved to England to learn the language and to study at the University of London chemistry. In 1969, he received his bachelors degree at Bedford College, he received his doctorate under professors Franz Sondheimer and Peter J. Garratt at University College London in 1972. Subsequently, he was post-doctoral fellow at Thomas J. Katz at Columbia University from 1973 to 1976 by Elias James Corey Jr. at Harvard University. From 1976 to 1989 he worked at the University of Pennsylvania from assistant professor to the Rhodes -Thompson Professor of Chemistry up. In 1989 he moved as a chemistry professor at the University of California, San Diego and at the same time as Darlene Shiley Professor of Chemistry and Chair of the Department of Chemistry at the Scripps Research Institute. Since 1996 he has also Aline W. and L. S. Skaggs Professor of Chemical Biology at the same institute.

Nicolaou works in the field of organic chemistry, especially in the synthesis of organic and natural products, including many pharmacologically interesting molecules such as paclitaxel (Taxol ) ( 1994), epothilone A and B ( 1996), eleutherobin and Sarcodictyin A (both 1997) and vancomycin (1999 ), whose total synthesis succeeded.

On July 15, 1973 married Georgette Nicolaou Karayianni, with whom he has four children: Colette, Alexis, Christopher and Paul.

Publications

Nicolaou published about 600 scientific papers and is involved in more than 50 patents.

  • NA Petasis: Selenium in Natural Products Synthesis. CIS Inc., Philadelphia, 1984, ISBN 0-914891-00-6.
  • Erik J. Sorensen Classics in Total Synthesis. Targets, Strategies, Methods. Wiley-VCH, 1996, ISBN 3-527-29231-4.
  • By Scott A. Snyder: Classics in Total Synthesis II More Targets, Strategies, Methods. Wiley- VCH, 2003, ISBN 3-527-30684-6.
  • With Tamsyn Montagnon: Molecules That Changed the World. Wiley -VCH, Weinheim, Bergstr 2006, ISBN 3-527-30983-7

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