Michael Rosbash
Michael Rosbash Morris ( born 1944 in Kansas City, Missouri) is an American molecular biologist and Chrono and professor at Brandeis University in Waltham, Massachusetts.
Life
The parents of Michael Rosbash had to leave Germany in 1938. The family moved from Kansas City to Boston, Massachusetts when Michael was still a toddler. Rosbash studied chemistry at the California Institute of Technology (Caltech ) in Pasadena, California. However, after an internship at Norman Davidson, he began to be interested in biology more. Rosbash acquired in 1965 as the bachelor degree. After a year as a Fulbright scholar at the Institute de biologie physico- Chimique in Paris, he went to the Massachusetts Institute of Technology (MIT ) in Cambridge, Massachusetts, where he in 1970 a Ph.D. acquired in biophysics. As a postdoctoral fellow Rosbash worked at the University of Edinburgh in Scotland. Since 1973 it belongs to the faculty of Brandeis University in Waltham, Massachusetts. Currently (as of 2011 ), he is a professor of biology and director of the National Center for Behavioral Genomics (National Centre for Behavioral Genetics ). Rosbash still has a Professor of Molecular Biology at Massachusetts General Hospital at Harvard University in Boston. Since 1989, Rosbash research in addition to the Howard Hughes Medical Institute ( HHMI ).
Work
Rosbash made outstanding contributions to the study of RNA processing and the circadian rhythm. Together with Jeffrey Hall could Rosbash first time in 1984 with a period " Verhaltensgen " of the circadian rhythm clone. Her work has subsequently led to the identification and functional analysis of the proteins that underlie the biological clock of the fruit fly (Drosophila melanogaster ). Hall and Rosbash proposed a negative feedback of the transcription mechanism of the biological clock. The model is still valid and could be applied to all living things, including humans. The chronotherapy is considered potential application of research results in people with sleep disorders. Recent work Rosbashs deal with the relationship of the pacemaker of the biological clock in fruit flies with the change of light and darkness as well as the neural circuits that underlie the change of activity and rest.