Neural crest

The training of the neural crest is an intermediate step in neurulation an embryo and comes only with the phylum of Chordata, which also includes the vertebrates (vertebrates ), are available.

The neural crest is formed by folding of the ectoderm. From this channel-like structure formed by progressive neurulation the neural tube, which is located between the epidermis and the notochord. The neural crest is represented by bilateral ( two-sided ) cell lines in the area of the beads of the embryonic neural tube, which join together. Neural crest cells then migrate to distant sites in the embryo, where they incur different structures such as parts of the teeth or jaw elements of the cartilage and structures of the peripheral nervous system (e.g., sensory cells of the skin and Schwann cells). From neural crest cells and melanocytes and adrenal medulla are formed.

Where this is not the innervation of the large intestine by neural crest cells ( aganglionosis ), which can lead to megacolon.

• Organogenesis