Olaflur

  • N, N, N'- tris (2- hydroxyethyl) -N'- octadecyl -1, 3 - diaminopropandihydrofluorid
  • N-( N, N -bis ( hydroxyethyl) -aminopropyl) - N -hydroxyethyl - octadecylamine dihydrofluoride

A01AA03

Kariesprophylaktikum

Fixed

Template: Infobox chemical / molecular formula search available

Olaflur ( INN) is a drug that is used for the prevention of dental caries and periodontal disease.

Chemically, it is the dihydrofluoride a long-chain tertiary diamine. Olaflur counts to the group of amine fluorides.

Use

Olaflur is used for the prevention of caries and periodontal disease since 1966. Here, concentrations of 500 ppm for children's and 1250 ppm for " adult" toothpaste satisfy ( calculated as fluoride). According to the GfK drug index, the average daily dose ( defined daily dose eng. DDD) is 1.1 mg (calculated as fluoride).

Toxicology

Like any other material are also fluorides incorrect dosage toxic. With durable overdose they can be stored in the bones and modify their properties. Overdose in the first years of life, before the permanent teeth are developing can lead to dental fluorosis, a discoloration and weakening of the set have hard tissue of the teeth.

Trade names

Aminomed (D), Elmex (D, A, CH), Ledermix fluoride gel (D), Friscodent Multicare (D)

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Dangerous Substances Directive (67/548/EEC)
615473
de