Oligoclonal band

The concept of oligoclonal bands plays a role in the diagnosis of cerebrospinal fluid ( CSF). In the isoelectric focusing to provide immunoglobulins of the IgG type as bands; If the CSF compared to the serum, show increased bands, this allows us to conclude on an immunoglobulin synthesis in the central nervous system. This is an indication of an inflammation process taking place there, such as in multiple sclerosis.