Oligonucleotide

Oligonucleotides (from the Greek oligo = few ') are from a few nucleotides (DNA or RNA) constructed oligomers. The nucleotide sequence consisting of 4 to 10 nucleotide units.

Oligonucleotides are used as

  • Antisense oligonucleotides
  • Oligonucleotide DNA Fingerprinting
  • Oligonucleotide probe
  • Oligonucleotide chip
  • Mutagenesis or cassette mutagenesis primers in the Oligonukleotidvermittelten (English oligonucleotide mediated mutagenesis )
  • Primers for the polymerase chain reaction

In vitro produced oligonucleotides and aptamers are called.

Synthesis

The oligonucleotides are synthesized by the phosphoramidite method of solid phase ( solid phase synthesis).

Polynucleotide
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