Panthenol

  • ( ) - (R ) -2,4 -dihydroxy- N-(3 -hydroxypropyl) - 3,3- dimethylbutyramide
  • Provitamin B5
  • PANTHENOL (INCI)

D03AX03 S01XA12

1.2 g · cm -3

118-120 ° C (at 2.7 Pa)

Miscible with water

1.497 (20 ° C)

15 g · kg -1 ( LD50, mouse, oral)

Template: Infobox chemical / molecular formula search available

Dexpanthenol (also known as pantothenol, D-panthenol or panthenol hereinafter) is a chemical compound which is one of the polyols, and amides. The connection has long been used medicinally as a topical agent in the treatment of diseases of the skin and mucous membranes, and cosmetically in medical skin care.

Provitamin

Panthenol is a provitamin, a precursor of a vitamin of the B vitamins, it is in the body to pantothenic acid (vitamin B5) converted.

Pantothenic acid is a constituent of coenzyme A, and thus plays an important role in skin metabolism.

Properties and application areas

Panthenol is well absorbed in water -oil emulsions of the skin and accumulates at the application site. It increases the moisture holding capacity of the skin and thus has nourishing properties and improves skin elasticity. It supports the formation of new skin cells and thus contributes to regeneration. In addition, panthenol also has antipruritic, anti-inflammatory and wound-healing properties.

The drug is used by many manufacturers as an ingredient for skin creams, ointments and shampoos or even for lozenges, nasal sprays, eye drops and contact lens cleaning products. Furthermore, panthenol is used for healing of new tattoos copperplate. Also applies the active ingredient in the aquarium, where he is employed as a component of Crustacea - care products and to support the moulting process of animals.

Side effects

Panthenol is generally very well tolerated. In very rare cases, it may cause irritation, redness, or contact allergies. Through an allergy test is repeated if necessary after eight days in order to avoid sensitization through your initial contact, such an allergy can be detected.

Trade names

Bepanthen (D, A, CH), Bepanthol, Corneregel (D, A), Marolderm (D), nasal spray Ratiopharm Panthenol (D), nasic -cur (D), Pan - Ophtal (D), Panthenol foam spray (D, A, CH, I), various generics (D)

Addivit (D), Bepanthen Antiseptic wound cream ( D), Bepanthen plus (A, CH), Cernevit (D, A), Colda Balm (A), Dispatenol (D), Dolobene (D, A), Inzolen (D), Pantozet (A), Siccaprotect (D, A), Venobene (A)

International Nomenclature of Cosmetic Ingredients CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Itch Wound healing Orally disintegrating tablet Crustacean Skin allergy test CRC Handbook of Chemistry and Physics Integrated Authority File
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