Peyer's patch

The Peyer's patches, and Peyer's patches, pile or plates ( Folliculi lymphatici aggregati ) called, are contiguous accumulations of 10 to 50 follicles. They come across the small intestine before, but they are most common in the ileum (ileum ) and can be found in appendix. They are visible from the outside through the intestinal wall than about 1 cm structures. They are named after the Swiss anatomist Johann Conrad Peyer ( 1653-1712 ).

Function

Peyer's patches are part of the lymphatic system, are part of the so-called MALT system ( mucosa associated lymphoid tissue, engl. For " mucosa - associated lymphoid tissue" ) or more specifically the GALT ( gut-associated lymphoid tissue, engl. For " gut - associated lymphoid tissue " ) and play an important role in the defense against infection in the gut and in the proliferation of immunological information as a collection of cells of the special adaptive immune system.

Tissue structure / histology

The Peyer's patches are usually compared with the Gekröseansatz ( mesentery ) in the submucosa and the lamina propria of the mucous membrane ( tunica mucosa ). Where the follicles extend into the mucosa, lacking the usual villi and crypts. Attached to it is dome-like bulging in the lumen of points which are therefore also referred to as a dome, contains so-called M cells. They lead, for example, viruses and bacteria through their cell bodies in the follicles continue ( transcytosis ), thereby triggering an immune response.

In ruminants, Peyer's patches are apparently the bursa equivalent organ.

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