Phenacyl bromide
- Phenacyl bromide
- 2- bromoacetophenone
- α -bromoacetophenone
- Phenacyl halide ( ambiguous )
Colorless solid
Fixed
1.65 g · cm -3
51 ° C.
260 ° C
16 hPa ( 134 ° C)
- Insoluble in water
- Insoluble in ethanol, chloroform and diethyl ether
Risk
Template: Infobox chemical / molecular formula search available
ω -bromoacetophenone is a severe eye irritant chemical compound that is set back in their eye irritancy only slightly behind chloroacetophenone.
History
ω -bromoacetophenone was first mentioned in 1871 by A. Emmerling and C. Engler.
Production and representation
ω -bromoacetophenone is obtained by bromination of acetophenone.
Properties
Chemically speaking, ω -bromoacetophenone a mixed aliphatic- aromatic ketone. As a pure substance ω -bromoacetophenone is in the form of colorless rhombic crystals, the technical product is colored yellow-brown. The production is possible by bromination of acetophenone or by the Friedel -Crafts acylation of benzene with bromoacetyl bromide in the presence of aluminum chloride as a catalyst.
The melting point is at about 50 ° C, the boiling point is about 133 ° C. In case of contact with ω -bromoacetophenone flushing of the eyes is necessary.
Use
ω -bromoacetophenone is used mainly as an intermediate for preparation of pharmaceuticals and other chemical compounds (for example, of indoles by Bischler - Möhlau indole synthesis ).