Phosphodiester bond

Phosphodiester bonds form the cohesion in the backbone of DNA and RNA. The nucleotides from which they are constructed, initially wear it only on the carbon atom C5 of the underlying pentose a phosphoric acid residue, the chemical terms, an ester of phosphoric acid with the alcoholic OH group is at this carbon atom. In the chain extension during the transcription of RNA or replication of DNA is a second ester bond is based on the existing phosphoric acid residue is closed with the OH group on the carbon atom of C3 of ribose or deoxyribose, whereby the 3'-5 ' phosphodiester bond is formed.

• Chemical Bonding