Phosphodiesterase
Phosphodiesterases (PDE ), more precise 3 ', 5'- Cyclonukleotid phosphodiesterases, are a group of enzymes in vertebrates, the second messenger cAMP and cGMP to degrade AMP and GMP. A distinction eleven isoenzymes are localized in different tissues in the human body. Phosphodiesterases can by various drugs called phosphodiesterase inhibitors (a type of enzyme) are inhibited nonspecific or specific. A widely used non-selective phosphodiesterase inhibitor, for example, caffeine.