Proflavine

3.6 diaminoacridine

  • 92-62-6
  • 952-23-8 (hydrochloride)
  • 1811-28-5 ( hemisulfate salt hydrate )

Yellow solid

Fixed

  • 284-286 ° C
  • 270 ° C (hydrochloride)

9.7

  • Readily soluble in ethanol and water: 500 g · l-1
  • Insoluble in benzene and ether

Hemisulfatsalzhydrat

Attention

Hemisulfatsalzhydrat

Template: Infobox chemical / molecular formula search available

Proflavine is an aromatic heterocyclic compound. At room temperature it exists as a brown - green powder. The structure is based on a proflavine, acridine skeleton. Sold as proflavine hemisulfate and or chloride is used as an antiseptic and disinfectant.

Properties

The melting point of proflavine is located at 285 ° C. It is readily soluble in water, as in aqueous solution, the heterocyclic nitrogen atom is protonated. Thus, the proflavine is present ionic. It shows yellow fluorescence in aqueous solution. The absorption maximum of proflavine is in aqueous solution and at a pH value of 7 at 450 nm

Introduced into the organism acts as proflavine intercalator in the DNA, and is therefore potentially mutagenic.

Swell

  • Silke grain, Michael W. exchange: Laboratory Simulation for Coupled Cycles of Phtotosynthesis and respiration. In: Journal of Chemical Education. Vol 78 No. 9, September 2001; doi: 10.1021/ed078p1238.
CAS registry number PubChem Dangerous Substances Directive (67/548/EEC) Digital Object Identifier Integrated Authority File
662046
de