Quinolizidine

Octahydro -2H- quinolizidine

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Quinolizidine has the structure of a nitrogen-containing heterocycle. It can also be described as the tertiary amine. It thus has weakly basic properties and is capable of salt formation.

Occurrence

Some well-known alkaloids, such as cytisine, sparteine ​​or lupinine that occur in leguminous plants such as lupines, contain a quinolizidine basic structure. Another representative of pharmaceutical use would be as ajmaline.

Synthesis

They can be constructed stereoselectivity of α - acyliminium ion in a manner olefin carbocyclization.