Releasing-Hormone

Releasing hormones, also Liberine, are neuropeptides that are formed in certain core areas in the hypothalamus. The nerves terminate in the median eminence ( a Neurohämalorgan at the bottom of the hypothalamus ). Here, the releasing hormones are released into the blood vessels under the control of other hormones and neurotransmitters, ranging directly to the anterior pituitary. One speaks of a portal system. In the pituitary gland releasing hormones stimulate the release of other hormones. Somatostatin and dopamine release Inhibiting Hormone ( statins), so regulators that suppress the release. The formation of the hormones of the pituitary gland is not under the control of the releasing hormones, only their release:

The hypothalamic releasing hormones of the people and their effect

• TRH ( thyrotropin releasing hormone), and Thyreoliberin, causes the release of thyrotropin (TSH) and prolactin.
• CRH ( corticotropin releasing hormone), corticotropin also causes the release of adrenocorticotropin (ACTH).
• GnRH ( Gonadotropin -releasing hormone ), and gonadoliberin, the release of follicle stimulating hormone ( FSH) and luteinising hormone causes (LH).
• GHRH ( Growth hormone releasing hormone ), and Somatoliberin, causes the release of somatotropin (growth hormone, growth hormone, GH).
• PRH (prolactin -releasing hormone ) there is not according to the state of science. Although the prolactin - releasing peptide ( PrRP ) (from the pituitary, ) can reach prolactin release in cell culture, but where the other releasing hormones are released into the portal system to be then transported to the pituitary gland in the median eminence, you do not find the PrRP neurons. Therefore, there are serious doubts whether the pituitary prolactin release is stimulated by PrRP. Prolactin release is under the negative regulation of dopamine ( see below).

The hypothalamic Release Inhibiting Hormone of the people and their effect

• Somatostatin Together with Somatoliberin (growth hormone -releasing hormone ) Somatotostatin controls the release of the growth hormone. In addition, there is a regulator of other hormone releases in the islet of Langerhans cells and in the stomach and intestinal tract.
• Dopamine: Unlike the above neuropeptides is no dopamine neuropeptide, but as a derivative of tyrosine, a catecholamine. It acts both as a neurotransmitter and as a hormone. Released from the median eminence and transported via the portal system to the pituitary gland, it suppresses the hormone prolactin release.