Seroconversion

Seroconversion is the medical term for the development of specific antibodies against antigens of a foreign body in the context of infection or vaccination, and the antibody class switching in the course of an infection of IgM (early antibody) to IgG (late antibody). It involves the serological response of the immune system.

Seroconversion after a previously negative detection assay for IgG antibody is positive. Antigens of the foreign matter, however, are generally not detectable. Applied this test, for example in the diagnosis of HIV, since it - is relatively inexpensive - compared to a PCR.

• Immunology