Silylation

Silylation under refers to chemical reactions in organic chemistry, in which the products are derived from derivatives of silanes ( derivatization ). Of special importance is the silylation to form a siloxane bond (Si -O -Si) in the production of silicone materials. The silylation of hydroxyl groups in alcohols is carried out with alkyl or Arylsiliciumchloriden and is an important functionalization of organic chemistry. Since the silyl group from the products formed can be easily removed again, it is referred to herein as a protecting group. The silylation of enolates with trimethylchlorosilane (abbreviated TMS -Cl) provides TMS -protected enols.

A related reaction is the hydrosilylation, to be implemented by a catalytic addition reaction of vinyl groups or other multiple bonds in derivatives of hydrosilanes. Typical catalysts are complexes of the precious metal platinum. This type of reaction is varied in the rubber manufacturing application.

For many classes of substances such as carbohydrates, long-chain alcohols, phenols, sterols, steroids and fatty acids, silyl derivatives play an important role in the gas chromatographic analysis, as the derivatives produced without decomposition are usually vaporized and can be particularly well separated on nonpolar stationary phases.

Silylating

• Aminopropyltriethoxysilane ( APTES )
• Dichlorodimethyl
• Chlorotrimethylsilane
• Hexamethyldisilazane
• N-methyl- N-( trimethylsilyl) - trifluoroacetamide ( MSTFA )
• N, O-bis (trimethylsilyl) acetamide (BSA)
• N, O-bis ( trimethylsilyl) trifluoroacetamide ( BSTFA )
• N -trimethylsilyl -diethylamine ( DEA TMS )

References

• Silylation and catalytic amination of cellulose in ammonia, ISBN 3-8265-9643-9