Stefanie Dimmeler

Stefanie Dimmeler ( born July 18, 1967 in Ravensburg, Germany ) is a German biologist and biochemist. She received the 2005 doped with 1.55 million euros Gottfried Wilhelm Leibniz Prize for their research on programmed cell death of endothelial cells of man.

Life

Stefanie Dimmeler attended schools in Hagnau and Stetten and high school in the village of Mark. From 1986 to 1991 she studied biology at the University of Konstanz, where she completed her degree at the Department of Biological Chemistry 1991 Effect of Ebselen on Ca2 currents in human platelets. In 1993 she also received his doctorate in Konstanz Nitric oxide -stimulated ADP- ribosylation of Dr. rer. nat.

From 1993 to 1995, Dimmeler research assistant in the Biochemical and Experimental Division of the Surgical Department of the University of Cologne and then from 1995 to 2001 in the Department of Medicine, Division of Cardiology, University of Frankfurt am Main, where since 1997 the research group "Molecular Cardiology "derives. In 1998 she became a professor in Experimental Medicine about endothelial dysfunction in atherosclerosis - Studies on the apoptosis of endothelial cells. Since 2001 she has been a professor of Molecular Cardiology, University of Frankfurt. Since 2008 she has been director of the Institute for Cardiovascular Regeneration at the Center for Molecular Medicine, Goethe University of Frankfurt. From 2008 to 2012 she was a member of the German Ethics Council.

Research

Stefanie Dimmeler focuses its research primarily on the molecular investigation of endothelial cells, ie the cells, which form the lining of blood vessels. An important aspect is the apoptosis, also known as programmed cell death of the tissue. Dimmeler examined in this context the necessary messengers, the development of damage to these cellular structures as well as the ways to regenerate these processes. This basic research is to provide above all a better understanding of the processes involved in atherosclerosis and indicate this treatment options. They also gave some results on stem cell therapy with the help of progenitor cells from the bone marrow for the treatment of heart attack patients. Recent work also deal with the regulation of vascular growth and stem cells by small Genschnipselchen, called microRNAs.

Awards

Besides a number of scholarships and funds for research funding Stefanie Dimmeler was awarded the following prizes for their academic work:

Publications

• Stem cell therapy in cardiology. Status and perspectives. Edited together with Andreas Zeiher. Uni-Med, Bremen 2004 ISBN 9783895998003

For more information about publications: www.cardiovascular - regeneration.com and www.ncbi.nlm.nih.gov / pubmed