Thymidine

Colorless plates or needles

Fixed

188 ° C.

  • Soluble in water, methanol, hot ethanol, acetone and ethyl acetate,
  • Very slightly soluble in chloroform

2,512 mg · kg -1 ( LD50, mouse, ip)

Template: Infobox chemical / molecular formula search available

Deoxythymidine (dT ), often also called trivial thymidine, a nucleoside, from the nucleobase thymine and of the pentose D- deoxyribose.

Deoxythymidine is part of the deoxyribonucleic acid ( DNA). While the others appear deoxynucleosides as nucleoside in the same ribonucleic acid (RNA ), this is not the case for deoxythymidine; the nucleoside thymidine is incorporated herein by uridine substituted (see genetic code).

Deoxythymidine forms a base pair with deoxyadenosine.

Only in certain tRNA molecules the actual thymidine can be found ( ribothymidine ), but not in the rest of the RNA.

Isomers and analogues

  • Clevudin
  • Telbivudine
  • Azidothymidine (AZT )
CAS registry number PubChem Intraperitoneal injection Clevudine Zidovudine
258233
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