Total iron-binding capacity

The iron binding capacity ( FBC ) of blood serum is a now obsolete laboratory parameter for the assessment of iron metabolism. It has been replaced by the direct measurement of serum transferrin.

The SFBC checked how much iron is bound in the serum when iron is added in excess. This value is referred to as " total iron binding capacity " ( TIBC ) and Total Iron Binding Capacity ( TIBC ). A high TIBC corresponds to a high transferrin concentration. The latent or "free iron binding capacity " is the difference between the measured TIBC and serum iron. The free SFBC corresponds to the non-occupied with iron transferrin, ie the free iron binding sites in the blood fluid.

Reference range

  • TIBC: 270-420 μg/100ml
  • Free SFBC: 150-300 μg/100ml

The value indicates the amount of iron that is bound by 100 ml of serum.

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