Zbtb7

  • OMIM: 605 ​​878
  • UniProt: O95365

Zbtb7 ( Zinc finger and BTB domain-containing protein 7, originally Pokemon ) is a cancer- promoting protein in vertebrates, which is encoded by the gene ZBTB7 ( with localization on chromosome 19p13.3 ). The first discovery was published in Nature in 2005. The substance suppresses the transcription of certain proteins, and thus indirectly inhibits the function of the tumor suppressor p53 and RB.

The original name Pokemon stands for " POK erythroid myeloid ontogenic factor" and is a backronym of the Pokémon series of films and games. After a complaint from Nintendo and Pokémon USA in December 2005, the standard designation "Pokemon" was withdrawn, since it says " Zbtb7 ".

Human Genome Organisation Digital Object Identifier GameSpot
835068
de