4-Chloroaniline

The chloroanilines form a group of substances derived from both the aniline and from chlorobenzene in chemistry. The structure consists of a benzene ring with an added amino group (-NH2) and chlorine ( -Cl) as a substituent. Due to their different arrangement (ortho, meta or para), three constitutional isomers arise with the empirical formula C6H6ClN. In addition, also the isomeric N- chloroaniline exists.

Depending on the number of chlorine atoms ( one, two, three, four or five) also differentiates between mono-, di -, tri -, tetra -and penta- chlorinated anilines.

Properties

4-chloro aniline, which has the highest symmetry, has the highest melting point. All compounds of this group are classified as toxic and hazardous to the environment. Chloroanilines are generally used as intermediates for the synthesis of other chemical compounds such as pesticides, dyes, and drugs. Since the natural degradation of some of these substances are the free chloroanilines used in the synthesis (or even with improper production ), traces the connections are to be found ( in the last few decades to an even smaller extent ) in groundwater and rivers. The detection of the substances can be carried out via liquid chromatography.

Use

Chloroanilines are generally used as intermediates for the synthesis of other chemical compounds such as pesticides, dyes, and drugs. 4-chloroaniline may after reductive cleavage of azo groups not of textiles and leather articles which may come prolonged contact with the human skin directly in contact, to be released ( Appendix 1 of the Commodities Regulation ).