Affinity magnetic separation
The affinity magnetic separation (AMS, and magnetic affinity separation ), and in a laboratory procedures may be removed from body fluids or cell cultures with the bacteria effectively. It can also be used to quantify the pathogenicity of blood, food or feces. Another separation process is the immunomagnetic separation (IMS ), which is better suited for the isolation of eukaryotic cells.
Bacteriophages recognize their hosts by bacteria- binding proteins to the tail ends, which have a strong affinity to proteins or hydrocarbon structures on the host surface. Coated with these phage proteins paramagnetic beads bind specific cell components on the host surface, thereby catching these cells ( Phagenligand technology). Subsequently, a magnet is attached to the outer side of the test vessel, attracts the bound cells to the beads, and thereby concentrated.
- Separation processes