Albert Eschenmoser

Albert Eschenmoser (* August 5, 1925 in Erstfeld / Switzerland ) is a Swiss chemist.

Life

1949 Eschenmoser received his diploma as a scientist (graduate sc. ) And 1951 the Doctor of Science (D. Sci. ) Of the Swiss Federal Institute of Technology ( ETH), where in 1956 he lecturer in Organic Chemistry, 1960 ao Professor and in 1965 Full Professor of General Organic Chemistry was. Since 1992, Albert Eschenmoser professor emeritus of ETH Zurich. 1996 to 2009 worked as a Professor Eschenmoser ( Skaggs Institute for Chemical Biology ) at The Scripps Research Institute, La Jolla / California, USA.

In his research in organic and bioorganic chemistry has Eschenmoser contributions made ​​to the theory of the biosynthesis of terpenes, structure elucidation of natural products, stereochemistry and mechanism of organic chemical and bio - chemical reactions, development of new methods for organic synthesis, total synthesis of complex natural products (example: vitamin B12) as well as the chemical etiology of the structural type of the nucleic acids. He developed Eschenmoser fragmentation and the Eschenmoser salt discovered in his research group bear his name.

Volume 82 of the journal Heterocycles from the years 2010 and 2011, dedicated to Albert Eschenmoser is.

Albert Eschenmoser has been married since 1954, née Elisabeth Baschnonga and has one daughter ( Esther ) and two sons ( Jürg and Philip ).

Honors and Awards (selection)

Overall Eschenmoser has won 30 national and international academic awards, including the following:

  • Core Prize of ETH Zurich (1949 )
  • Werner Prize of the Swiss Chemical Society
  • Ruzicka Prize of the ETH Zurich (1958 )
  • Member of the Leopoldina (1976 )
  • Tetrahedron Prize for Creativity in Organic Chemistry (1981 )
  • Wolf Prize of the Wolf Foundation, Herzlia, Israel ( 1986)
  • Austrian Decoration for Science and Art (1993 )
  • Oparin Medal ( 2002)
  • Frank H. Westheimer Medal from Harvard University ( 2004)
  • Paul Karrer Medal of the University of Zurich (2008)

Publications (selection)

The scientific work of Albert Eschenmoser is unusually wide -ranging and includes more than 270 publications.

  • Albert Eschenmoser: acid-catalyzed cyclization to in mono-and sesquiterpene compounds. PhD thesis No 2018, 1952, ETH Zurich.
  • A. Eschenmoser, A. Frey: Over the cleavage of the Mesylesters of 2- methyl-2- oxymethyl -cyclopentanone with bases. In: Helv. Acta. 35, 1952, p 1660.
  • A. Eschenmoser, L. Ruzicka, O. Jeger, D. Arigoni: A stereochemical interpretation of the biogenetic isoprene rule for the triterpenes. In: Helv. Acta. 38, 1955, p 1890.
  • J. Schreiber, W. Leimgruber, M. Pesaro, P. Schudel, A. Eschenmoser: synthesis of colchicine. In: Angew. Chem. 71, 1959, pp. 637; Helv Chim. Acta. 44, 1961, p 540
  • A. Eschenmoser, Dorothee Felix, G. Ohloff: A novel fragmentation of cyclic α, β - unsaturated carbonyl systems; Synthesis of rac- exaltonee and muscone from Cyclododecanone. In: Helv. Acta. 50, 1967, p 708
  • Y. Yamada, D. Miljkovic, P. Wehrli, B. Golding, P. Löliger, R. Keese, K. Müller, A. Eschenmoser: A new synthetic access to the Corrin. In: Angew. 81, 1969, p 301; Angew. Chem Int. Ed. 8, 1969, p 343
  • L. Tenud, S. Farooq, J. Seibl, A. Eschenmoser: endocyclic SN reactions at saturated carbon? In: Helv. Acta. 53, 1970, p 2059th
  • A. Eschenmoser, CE Wintner: Natural Product Synthesis and vitamin B12. In: Science. 196, 1977, pp. 1410-1426.
  • A. Eschenmoser, Vitamin B12: Experiments Concerning the origin of its molecular structure. In: Angew. Chem 100, 1988, page 5; Angew. Chem Int. Ed. 27, 1988, pp. 5-39.
  • M. Bolli, R. Micura, A. Eschenmoser: pyranosyl - RNA: Chiroselective self-assembly of base sequences by league tive oligomerization of tetranucleotide -2 ', 3'- cyclic phosphates (with a commentary Concerning the origin of biomolecular homochirality ). In: Chemistry & Biology. 4 1997, pp. 309-320.
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