Alfons Maria Jakob

Alfons Maria Jakob ( born July 2, 1884 in Aschaffenburg, † 17 October 1931 in Hamburg ) was a German neurologist with important contributions in the field of neuropathology.

Life

Alfons Jakob studied medicine with a focus on neurology and psychiatry in Munich, Berlin and Strasbourg. The active Korporierte was co-founder in 1905 of the Catholic Student Association KDSt.V. Rappoltstein (Strasbourg ) in Cologne CV. At the former Kaiser- Wilhelm University in Strasbourg in 1908, he earned his doctorate with the work The pathogenesis of pseudobulbar palsy (apparent paralysis of the medulla oblongata ). After the doctor's license to practice in 1909, he began his clinical work with psychiatrist Emil Kraepelin and worked in the departments of Neuromorphology under Franz Nissl and Alois Alzheimer in Munich.

In 1911, Jacob Head of the Laboratory of Pathology at the State Hospital Friedrich Berg, from 1914 director of the anatomical department. After serving in World War I as head of the Neurological Department of Psychiatry of the military hospital in Brussels and I am nervous doctor Genesungsheim Malone. After the end of World War II, he made ​​his own in 1919 with his own practice in neurology. In 1919 he became a professor in neurology and psychiatry at the University of Hamburg. There he was appointed in 1924 professor of neurology.

Alfons Jakob explored the consequences of peripheral nerve injuries and the secondary nerve degeneration, the morphological changes in multiple sclerosis, Friedreich's ataxia, glioneuralen juvenile dystrophy ( Alpers' disease). In 1920, he discovered shortly after the Kiel neurologist Hans Gerhard Creutzfeldt - the cancellous Encephalopathy, known since 1922 Creutzfeldt- Jakob disease. He has published five monographs and over 150 articles in professional journals.

Jacob was a valued teacher and his laboratory attracted scientists from Japan, Russia, Italy and the USA.

Is named after Jacob:

  • Creutzfeldt- Jakob disease, the prion attributed to subacute encephalopathy.

Writings (selection )

  • The extrapyramidal disorders with special emphasis on the pathological anatomy and histology and the Pathopsychologie of movement disorders; In: Monographs of the total areas of neurology and psychiatry, Volume 37, Berlin, 1923.
  • Normal and pathological anatomy and histology of the cerebrum; Reprint of the Handbook of Psychiatry, Leipzig and Vienna, 1927-1928.
  • The cerebellum; In: Handbook of microscopic anatomy, Berlin, 1928.
  • The syphilis of the brain and its membranes; in: Oswald Bumke (eds. ): Handbook of mental illness. Berlin, 1930.
October 17 Friedreich's ataxia Hans-Gerhard Creutzfeldt Integrated Authority File
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