Anisidine

The Anisidines (also Methoxyaniline or Aminoanisole ) form in chemistry a group of substances that are both from anisole ( methoxybenzene ) and also derives from aniline. The structure consists of a benzene ring with an added methoxy ( - OCH3) and amino group (-NH2) as a substituent. Due to their different arrangement (ortho, meta or para), three constitutional isomers arise with the empirical formula C7H9NO. First and foremost, you can view them as a methoxy-substituted anilines.

The nitrided or halogenated derivatives are also referred to as Anisidinen. Do they contain an additional methyl group, they form the group of cresidines. Just as the Anisidines from ordinary registered anisole or phenetidines of phenetole deduce the naming for cresidines carried out in an analogous manner starting from cresol ( nitrogen-containing derivatives of the cresols ).

Properties

The Anisidines only have slightly different pKa values ​​compared to the aniline ( 4.603 ). They differ clearly in their melting points. The 4- anisidine, due to its symmetry the highest melting point and is a solid.

Use

Anisidine are intermediates in the preparation of azo dyestuffs and pharmaceuticals. The Anisidines serve as starting materials for the representation of chlorine, bromine and Iodanisole means of the Sandmeyer reaction. Ortho- Ansidin must not released from textiles or leather that prolonged periods of time with the human skin directly in contact are (Appendix 1 of the Consumer Goods Ordinance ) after reductive cleavage of azo groups.

By boiling the diazonium salts of the methoxyphenols can be represented.

It is also a component of a detection reagent in thin layer chromatography of monosaccharides.

Derivatives

• 4-methoxy -m-phenylenediamine ( CAS: 615-05-4 )
• The Nitroanisidine