Ann Wagner first attended the Cor Jesus Academy in her hometown of St. Louis and studied at the University of Missouri Business Administration afterwards. She was temporarily working as a business woman then. From 1990, she began a career in politics as a member of the Republican Party. In 1992, she was in Missouri Director of the Committee for the Re-election of President George Bush. From 1999 to 2005 she was a state chairman of her party. Between 2001 and 2004 she was Deputy National Chairman ( Co - Chair ) of the Republicans. In 2004, she supported the campaign for the reelection of President George W. Bush. This they proclaimed in 2005 as the successor of Peter Terpeluk to the U.S. Ambassador to Luxembourg. This position she held until 2009. In 2010, she was Chair of the Election Committee of Roy Blunt in his successful candidacy for the U.S. Senate.
In the congressional elections of 2012, Wagner was in the second electoral district of Missouri in the U.S. House of Representatives in Washington DC chosen, where they succeeded the unsuccessful candidates for the Senate Todd Akin on January 3, 2013. There she is a member of the Finance Committee.
Ann Wagner is with Ray Wagner, a former director of the tax authority of Missouri, married. The couple has three children.