Antifibrinolytic

Antifibrinolytic agents act by inhibition of fibrinolysis in the blood, i.e., they cause a reduced degradation of the thrombus, and thus an increased clotting.

They are used therefore in an increased fibrinolysis in a strong fibrinolytic therapy and in case of complications during birth.

Pharmaceuticals

• Aprotinin: inhibits plasmin, kallikrein, trypsin, chymotrypsin. The onset of action is rapid.
• Aminocaproic acid, para- aminomethyl benzoic acid ( PAMBA ), tranexamic acid: Inhibition of plasminogen activators. The onset of action is slow here.

• Therapeutic procedures in hematology and oncology