Arecoline

• 63-75-2 ( arecoline )
• 300-08-3 ( arecoline hydrobromide · )
• 61-94-9 ( arecoline · hydrochloride)
• 900-77-6 ( arecoline · Acetarsol )

Parasympathomimetic

169-171 ° C ( arecoline hydrobromide · )

• Soluble in chloroform ( arecoline )
• Slightly soluble in chloroform and ether ( arecoline hydrobromide · )
• Soluble in water and ethanol ( arecoline hydrobromide · )

Hydrobromide

Risk

Template: Infobox chemical / molecular formula search available

Arecoline is in the seeds of betel nuts naturally occurring substance from the group of alkaloids.

It was first isolated in 1888 by Ernst Jahn. Arecoline is the methyl ester of Arecaidins and acts on the autonomic nervous system acetylcholine receptor agonist. The earlier use of worming of dogs is obsolete today. Were processed Arzneilich the water-soluble salts ( Arecolinhydrobromid, Arecolinhydrochlorid ).

The oily fluid has a density of 1.049 g · cm -3 and a boiling point of 209 ° C. It is soluble in ether and water. The synthesis takes place in several steps consisting of formaldehyde, acetaldehyde and methyl amine.

Arecoline has a similar effect as the nicotine, but this acts primarily on the Nicotinic acetylcholine receptor. Arecoline but is a known partial agonist of muscarinic acetylcholine receptor on the acetylcholine receptors M1, M2, M3 and M4 receptors work and which one makes for the parasympathetic primarily effects ( as Pupillenkonstriktion ( sphincter pupillae ), bronchial constriction, etc.) of the alkaloid responsible.