Arthur L. Horwich

Arthur L. Horwich ( born 1951 ) is an American cell biologist. He teaches and conducts research as a professor of genetics and pediatrics at Yale University and the Howard Hughes Medical Institute.

Life and work

Arthur Horwich was born in 1951 and grew up in Oak Park, a western suburb of Chicago, on. As a child he was a radio amateur, but turned already in high school of medicine. From 1969 he studied at Brown University, where he earned a Bachelor in 1972. He investigated the metabolism of fat cells and received in 1975 - as the best in his class - the conclusion as a Medical Doctor. Then he trained in the field of child and adolescent medicine on. He worked for three years as a post-doctoral fellow at the Salk Institute for Biological Studies in the field of molecular biology and virology, before he went back in 1981 as a postdoctoral fellow in medical genetics at the Yale University Medical School. With his mentor, Leon Rosenberg he cloned there ornithine transcarbamylase (OTC). In 1984 he became assistant professor in the Department of Genetics and built his own laboratory. There, he managed to produce 1987 OTC in yeast. To Horwichs main field of research protein folding developed. In 1989 he was able to provide evidence that chaperone proteins fold and has carried out many further studies on heat shock protein GroEL. Since 1990 he is also conducting research at the Howard Hughes Medical Institute and in 1995 he became full professor at Yale.

Arthur Horwich and his wife Martina, have three children.

Awards

  • Basil O'Connor Research Award
  • 2001: Hans Neurath Arward (Protein Society)
  • 2003: election to the National Academy of Sciences
  • 2004: Gairdner Foundation International Award ( Gairdner Foundation)
  • 2006: Stein and Moore Award (Protein Society)
  • 2007: Wiley Prize in Biomedical Sciences
  • 2008: Rosenstiel Award for Distinguished Work in Basic Medical Science
  • 2011: Albert Lasker Award for Basic Medical Research
  • 2011: Massry Prize with Franz -Ulrich Hartl
  • 2012: Shaw Prize in Life Science and Medicine
  • 2013: Herbert Tabor Research Award with Franz -Ulrich Hartl
Oak Park (Illinois) Hsp60 Digital Object Identifier Informationsdienst Wissenschaft
81214
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