Autonomously replicating sequence

An ARS element ( autonomously replicating sequence ) is a nucleotide sequence on DNA, on the replication is initiated.

ARS elements were discovered in plasmids of the yeast Saccharomyces cerevisiae that were independent in addition to the replication of the actual genome able to replicate itself. It is now known that such sequences also in the actual genome serve as a starting point ORI ( origin of replication ) of replication.

A typical single- ARS consists of about 150-200 nucleic bases, with eukaryotic ARS fail complicated and in mammals much larger. Typically, the ARS element is an A / T- rich region.

  • Genetics
Unicellular organism Adenine
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